Small molecule microarray screening methodology based on surface plasmon resonance imaging

In order to increase the scope and utility of small molecule microarrays (SMMs) we have combined SMMs and SPRi to screen small molecule antagonists against protein targets. Several small molecules, including immunosuppressive drugs (rapamycin and FK506) and reported inhibitors (FOBISIN and Blapsin)...

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Bibliographic Details
Main Authors: Vikramjeet Singh, Kuldeep Singh, Amita Nand, Huanqin Dai, Jianguo Wang, Lixin Zhang, Alejandro Merino, Jingsong Zhu
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Arabian Journal of Chemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535214003724