Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: The involvement of GRP78 and CHOP

Gastrodia elata Blume and its pure compounds protect BV-2 microglial-derived cell lines against β-amyloid: The involvement of GRP78 and CHOP

Objectives: Gastrodia elata (GE) Blume (Orchidaceae) has been previously known for its therapeutic benefits against neurodegenerative diseases. Microglial activation and death have been implicated in the pathogenesis of a variety of neurodegenerative diseases, including Alzheimer's disease. In...

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Bibliographic Details
Main Authors: Lee Geum-Hwa, Kim Hyung-Ryong, Han Sang-Yong, Bhandary Bidur, Kim Do-Sung, Kim Min-Gul, So Byung-Ok, Kim Sun-Young, Jo Kyu-Sik, Lee Bo-Hee, Seo Hee-Nam, Chae Soo-Wan, Chae Han-Jung
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Biological Research
Subjects:
Gastrodia elata
4HBA
GRP78
CHOP
β-amyloid
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400013&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400013&lng=en&tlng=en

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