Molecular Mechanisms of Hemoglobin F Induction
Hemoglobin F (HbF, α2γ2) is a major contributor to the clinical heterogeneity and ameliorating agent observed in patients with the β-globin disorders including β-thalassemia and sickle cell disease (SCD). During fetal life, HbF is the major hemoglobin but is largely substituted by adult hemoglobin (...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2011-12-01
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Series: | International Journal of Hematology-Oncology and Stem Cell Research |
Subjects: | |
Online Access: | https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/289 |