Molecular Mechanisms of Hemoglobin F Induction

Hemoglobin F (HbF, α2γ2) is a major contributor to the clinical heterogeneity and ameliorating agent observed in patients with the β-globin disorders including β-thalassemia and sickle cell disease (SCD). During fetal life, HbF is the major hemoglobin but is largely substituted by adult hemoglobin (...

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Bibliographic Details
Main Authors: Majid Farshdousti Hagh, Ali Dehghani Fard, Najmaldin Saki, Mohammad Shahjahani, Saied Kaviani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2011-12-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/289