Allosteric Modulation of αβδ GABAA Receptors

GABAA receptors mediate the majority of the fast inhibition in the mature brain and play an important role in the pathogenesis of many neurological and psychiatric disorders. The αβδ GABAA receptor localizes extra- or perisynaptically and mediates GABAergic tonic inhibition. Compared with synaptical...

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Bibliographic Details
Main Author: Hua-Jun Feng
Format: Article
Language:English
Published: MDPI AG 2010-11-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/3/11/3461/