Association of TIM-3 expression with glucose metabolism in Jurkat T cells

Association of TIM-3 expression with glucose metabolism in Jurkat T cells

Abstract Background T cell activation is associated with increase in glycolysis and glutaminolysis. T cell immunoglobulin and mucin domain containing protein-3 (TIM-3), a T cell surface molecule, downregulates T cell activation and leads to insufficient immunity in cancer and chronic infection. TIM-...

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Bibliographic Details
Main Authors: Mi Jin Lee, Su Jin Yun, Bokyoung Lee, Eun Jeong, Gyesoon Yoon, Kyongmin Kim, Sun Park
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Immunology
Subjects:
HAVCR2
Glycolysis
CD4+ T cell
Glutaminolysis
Glucose transporter
Online Access:http://link.springer.com/article/10.1186/s12865-020-00377-6

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http://link.springer.com/article/10.1186/s12865-020-00377-6

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