SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity

SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity

Abstract Background Multiple sclerosis (MS) is a chronic, debilitating condition characterized by CNS autoimmunity stemming from a complex etiology involving both environmental and genetic factors. Our current understanding of MS points to dysregulation of the immune system as the pathogenic culprit...

Full description

Bibliographic Details
Main Authors: Patrick O’Connell, Maja K. Blake, Sarah Godbehere, Andrea Amalfitano, Yasser A. Aldhamen
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Journal of Neuroinflammation
Subjects:
SLAMF7
CD319
CRACC
Multiple sclerosis
B cells
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-022-02594-9

Internet

https://doi.org/10.1186/s12974-022-02594-9

Similar Items