GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System

Cell-based therapies hold great promise for a myriad of clinical applications. However, as these therapies move from phase I to phase II and III trials, there is a need to improve scale-up of adherent cells for the production of larger good manufacturing practice (GMP) cell banks. As we advanced our...

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Bibliographic Details
Main Authors: Revathiswari Tirughana, Marianne Z. Metz, Zhongqi Li, Christine Hall, David Hsu, Jim Beltzer, Alexander J. Annala, Diana Oganesyan, Margarita Gutova, Karen S. Aboody
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050118300524