Involvement of Th1Th17 Cell Subpopulations in the Immune Responses of Mothers Who Gave Birth to Children with Congenital Zika Syndrome (CZS)

High levels of T helper 17 cell (Th17)-related cytokines have been shown in acute Zika virus (ZIKV) infection. We hypothesized that the high levels of Th17-related cytokines, associated with a regulatory environment during pregnancy, create a favorable milieu for the differentiation of CD4+Th17 cell...

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Main Authors: Iury Amancio Paiva, Débora Familiar-Macedo, Jéssica Badolato-Corrêa, Fabiana Rabe Carvalho, Helver Gonçalves Dias, Alex Pauvolid-Corrêa, Caroline Fernandes dos Santos, Andréa Alice Silva, Elzinandes Leal de Azeredo, Renata Artimos de Oliveira Vianna, Claudete Aparecida Araújo Cardoso, Alba Grifoni, Alessandro Sette, Daniela Weiskopf, Luzia Maria de-Oliveira-Pinto
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/2/250