Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8<sup>+</sup> T Cells in Non-Melanoma Cancers Compared to Melanoma

Qualitative Analysis of Tumor-Infiltrating Lymphocytes across Human Tumor Types Reveals a Higher Proportion of Bystander CD8<sup>+</sup> T Cells in Non-Melanoma Cancers Compared to Melanoma

<i>Background:</i> Human intratumoral T cell infiltrates can be defined by quantitative or qualitative features, such as their ability to recognize autologous tumor antigens. In this study, we reproduced the tumor-T cell interactions of individual patients to determine and compared the q...

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Bibliographic Details
Main Authors: Aishwarya Gokuldass, Arianna Draghi, Krisztian Papp, Troels Holz Borch, Morten Nielsen, Marie Christine Wulff Westergaard, Rikke Andersen, Aimilia Schina, Kalijn Fredrike Bol, Christopher Aled Chamberlain, Mario Presti, Özcan Met, Katja Harbst, Martin Lauss, Samuele Soraggi, Istvan Csabai, Zoltán Szállási, Göran Jönsson, Inge Marie Svane, Marco Donia
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
tumor-infiltrating lymphocytes
tumor microenvironment
immunotherapy
Online Access:https://www.mdpi.com/2072-6694/12/11/3344

Internet

https://www.mdpi.com/2072-6694/12/11/3344

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