Modification and inactivation of Cu,Zn-superoxide dismutase by the lipid peroxidation product, acrolein

Acrolein is the most reactive aldehydic product of lipidperoxidation and is found to be elevated in the brain whenoxidative stress is high. The effects of acrolein on the structureand function of human Cu,Zn-superoxide dismutase (SOD) wereexamined. When Cu,Zn-SOD was incubated with acrolein, thecova...

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Bibliographic Details
Main Author: Jung Hoon Kang
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2013-11-01
Series:BMB Reports
Subjects:
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTI3MThAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xMSU1RDEzMTEyNzE4MjhfJTI4NTU1LTU2MCUyOUJNQl8xMy0xMzgucGRm