Modification and inactivation of Cu,Zn-superoxide dismutase by the lipid peroxidation product, acrolein
Acrolein is the most reactive aldehydic product of lipidperoxidation and is found to be elevated in the brain whenoxidative stress is high. The effects of acrolein on the structureand function of human Cu,Zn-superoxide dismutase (SOD) wereexamined. When Cu,Zn-SOD was incubated with acrolein, thecova...
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Format: | Article |
Language: | English |
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Korean Society for Biochemistry and Molecular Biology
2013-11-01
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Series: | BMB Reports |
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Online Access: | http://bmbreports.org/jbmb/pdf.php?data=MTMxMTI3MThAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xMSU1RDEzMTEyNzE4MjhfJTI4NTU1LTU2MCUyOUJNQl8xMy0xMzgucGRm |