CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

Abstract Background The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation alters the cardiac immune response and, when combined with short-term pharmacological CCR2 inhibition, resulted in diminish...

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Bibliographic Details
Main Authors: Praveen Vasudevan, Markus Wolfien, Heiko Lemcke, Cajetan Immanuel Lang, Anna Skorska, Ralf Gaebel, Anne-Marie Galow, Dirk Koczan, Tobias Lindner, Wendy Bergmann, Brigitte Mueller-Hilke, Brigitte Vollmar, Bernd Joachim Krause, Olaf Wolkenhauer, Gustav Steinhoff, Robert David
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Genome Medicine
Subjects:
Immunocompromised
Myocardial infarction
Machine learning
Macrophages
Single-cell
Cell therapy
Online Access:https://doi.org/10.1186/s13073-023-01213-3

Internet

https://doi.org/10.1186/s13073-023-01213-3

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