Effect of Alpha-Lipoic acidon Pancreatic Optic Atrophy1 (OPA1) Gene Expression in Male Rat Model of Obstructive Cholestasis and Cirrhosis

Backgroundand Aim: Cholestasis is characterized by blockade ofbile flowfrom the liver to the intestine, which leads to accumulation of bile acids within liver and plasma; it is associated withmetabolic disordersandcause hepatocellular necrosis and apoptosis during cholestatic liver diseases.Mitochon...

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Bibliographic Details
Main Authors: Khosrobakhsh Farnoosh, Moloudi Mohammad Raman, Shoja Khatere, Mohammadi Sahel
Format: Article
Language:fas
Published: Kurdistan University of Medical Sciences 2019-12-01
Series:مجله علمی دانشگاه علوم پزشکی کردستان
Subjects:
Online Access:http://sjku.muk.ac.ir/article-1-4892-en.pdf