Dynamic lung aeration and strain with positive end-expiratory pressure individualized to maximal compliance versus ARDSNet low-stretch strategy: a study in a surfactant depletion model of lung injury

Dynamic lung aeration and strain with positive end-expiratory pressure individualized to maximal compliance versus ARDSNet low-stretch strategy: a study in a surfactant depletion model of lung injury

Abstract Background Positive end-expiratory pressure (PEEP) individualized to a maximal respiratory system compliance directly implies minimal driving pressures with potential outcome benefits, yet, raises concerns on static and dynamic overinflation, strain and cyclic recruitment. Detailed accurate...

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Bibliographic Details
Main Authors: Congli Zeng, Min Zhu, Gabriel Motta-Ribeiro, David Lagier, Takuga Hinoshita, Mingyang Zang, Kira Grogg, Tilo Winkler, Marcos F. Vidal Melo
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Critical Care
Subjects:
ARDS
PEEP titration
Lung aeration
Tidal strain
Tidal recruitment
Online Access:https://doi.org/10.1186/s13054-023-04591-7

Internet

https://doi.org/10.1186/s13054-023-04591-7

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