Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice

Type I diabetes mellitus (T1DM) increases atherosclerotic cardiovascular disease; however, the underlying pathophysiology is still incompletely understood. We investigated whether experimental T1DM impacts HDL-mediated reverse cholesterol transport (RCT). C57BL/6J mice with alloxan-induced T1DM had...

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Bibliographic Details
Main Authors: Jan Freark de Boer, Wijtske Annema, Marijke Schreurs, Jelske N. van der Veen, Markus van der Giet, Niels Nijstad, Folkert Kuipers, Uwe J.F. Tietge
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Journal of Lipid Research
Subjects:
high density lipoproteins
bile acids
cardiovascular disease
atherosclerosis
neutral sterols
glucose
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520413501

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http://www.sciencedirect.com/science/article/pii/S0022227520413501

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