Glt25d2 Knockout Directly Increases CD25+CD69– but Decreases CD25–CD69+ Subset Proliferation and is Involved in Concanavalin-Induced Hepatitis

Background/Aims: The elaborate structure of the extracellular matrix (ECM) and the appropriate surface glycoforms upon it are indispensable to CD4+ T cell regulation. Methods: To explore the effects of Glcα1,2Galβ1 glycosylation mediated by GLT25D2 (Colgalt2) for CD4+ T cell regulation, we prepared...

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Main Authors: Xiaohua Hao, Ran Liu, Yifan Zhang, Yufeng Li, Qun He, Yubo Huang, Yu Jiang, Jiali Ma, Ping Li, Hongshan Wei
פורמט: Article
שפה:English
יצא לאור: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
סדרה:Cellular Physiology and Biochemistry
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גישה מקוונת:https://www.karger.com/Article/FullText/494546