Measurement of metoprolol solubility in supercritical carbon dioxide; experimental and modeling study
Metoprolol is a beta-blocker agent, widely used to treat hypertension, and some heart diseases. However, due to low bioavailability and short half-life of this drug, the dose and the frequency of its daily use are high, causes to some digestive problems in patients. Designing a new drug delivery sys...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Case Studies in Thermal Engineering |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214157X23000709 |