Measurement of metoprolol solubility in supercritical carbon dioxide; experimental and modeling study

Metoprolol is a beta-blocker agent, widely used to treat hypertension, and some heart diseases. However, due to low bioavailability and short half-life of this drug, the dose and the frequency of its daily use are high, causes to some digestive problems in patients. Designing a new drug delivery sys...

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Bibliographic Details
Main Authors: Saad M. Alshahrani, Amal M. Alsubaiyel, Maram H. Abduljabbar, Mohammed A.S. Abourehab
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Case Studies in Thermal Engineering
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214157X23000709