Does dexamethasone act in neuropeptides SP and CGRP in neurogenic inflammation of the skin? An experimental study

Does dexamethasone act in neuropeptides SP and CGRP in neurogenic inflammation of the skin? An experimental study

PURPOSE: To investigate the neuropeptides substance P (SP) and calcitonin gene-related peptide (CGRP) after subcutaneous injection of dexamethasone prior to skin incision in rats.METHODS:Twenty seven Wistar-EPM-1 rats were randomly divided into three groups. The sham group (SG) of rats was injected...

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Bibliographic Details
Main Authors: Jose Octavio Gonçalves de Freitas, Paulo Rogério Quieregatto, Bernardo Hochman, Guilherme Abbud Franco Lapin, Stella Maria Botequio Mella, Jessica Ruivo Maximino, Gerson Chadi, Lydia Masako Ferreira
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2015-08-01
Series:Acta Cirúrgica Brasileira
Subjects:
Calcitonin Gene-Related Peptide
Substance P
Neuropeptides
Dexamethasone
Neurogenic Inflammation
Skin
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000800523&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000800523&tlng=en

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