Identification of Senescence-Related Subtypes, the Development of a Prognosis Model, and Characterization of Immune Infiltration and Gut Microbiota in Colorectal Cancer

Identification of Senescence-Related Subtypes, the Development of a Prognosis Model, and Characterization of Immune Infiltration and Gut Microbiota in Colorectal Cancer

Cellular senescence is associated with tumorigenesis, and the subtype and prognostic signatures of senescence-related genes (SRGs) in the tumor microenvironment (TME) and gut microbiota have not been fully determined. Analysis of 91 SRGs obtained from the GSEA and MSigDB, and mRNA sequencing of gene...

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Bibliographic Details
Main Authors: Ju-Ji Dai, Yang-Yang Fu, Xi-Qiang Zhong, Wei Cen, Mao-Fei Ye, Xi-Han Chen, Yi-Fei Pan, Le-Chi Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Medicine
Subjects:
colorectal cancer
senescence
tumor microenvironment
gut microbiota
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.916565/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.916565/full

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