HPat a decapping activator interacting with the miRNA effector complex.

Animal miRNAs commonly mediate mRNA degradation and/or translational repression by binding to their target mRNAs. Key factors for miRNA-mediated mRNA degradation are the components of the miRNA effector complex (AGO1 and GW182) and the general mRNA degradation machinery (deadenylation and decapping...

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Bibliographic Details
Main Authors: Elisabeth Barišić-Jäger, Izabela Kręcioch, Stefanie Hosiner, Sanja Antic, Silke Dorner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071860&type=printable