Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion

Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion

Abstract Nonalcoholic steatohepatitis (NASH) is a progressive disorder with aberrant lipid accumulation and subsequent inflammatory and profibrotic response. Therapeutic efforts at lipid reduction via increasing cytoplasmic lipolysis unfortunately worsens hepatitis due to toxicity of liberated fatty...

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Bibliographic Details
Main Authors: Yoshito Minami, Atsushi Hoshino, Yusuke Higuchi, Masahide Hamaguchi, Yusaku Kaneko, Yuhei Kirita, Shunta Taminishi, Toshiyuki Nishiji, Akiyuki Taruno, Michiaki Fukui, Zoltan Arany, Satoaki Matoba
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39404-6

Internet

https://doi.org/10.1038/s41467-023-39404-6

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