The polySUMOylation axis promotes nucleolar release of Tof2 for mitotic exit

Summary: In budding yeast, the nucleolus serves as the site to sequester Cdc14, a phosphatase essential for mitotic exit. Nucleolar proteins Tof2, Net1, and Fob1 are required for this sequestration. Although it is known that these nucleolar proteins are SUMOylated, how SUMOylation regulates their ac...

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Bibliographic Details
Main Authors: Emily Gutierrez-Morton, Cory Haluska, Liam Collins, Raed Rizkallah, Robert J. Tomko, Jr., Yanchang Wang
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724008210