Antibody‐Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release

Antibody‐Drug Conjugates to Treat Bacterial Biofilms via Targeting and Extracellular Drug Release

Abstract The treatment of implant‐associated bacterial infections and biofilms is an urgent medical need and a grand challenge because biofilms protect bacteria from the immune system and harbor antibiotic‐tolerant persister cells. This need is addressed herein through an engineering of antibody‐dru...

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Bibliographic Details
Main Authors: Anne Tvilum, Mikkel I. Johansen, Lærke N. Glud, Diana M. Ivarsen, Amanda B. Khamas, Sheiliza Carmali, Snehit Satish Mhatre, Ane B. Søgaard, Emma Faddy, Lisanne deVor, Suzan H. M. Rooijakkers, Lars Østergaard, Nis P. Jørgensen, Rikke L. Meyer, Alexander N. Zelikin
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Advanced Science
Subjects:
antibody‐drug‐conjugates
antimicrobials
biofilms
drug targeting
Online Access:https://doi.org/10.1002/advs.202301340

Internet

https://doi.org/10.1002/advs.202301340

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