Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca<sup>2+</sup>-Activated K<sub>Ca</sub>3.1 Channels

Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca<sup>2+</sup>-Activated K<sub>Ca</sub>3.1 Channels

Duchenne muscular dystrophy (DMD) is an X-linked disease, caused by a mutant dystrophin gene, leading to muscle membrane instability, followed by muscle inflammation, infiltration of pro-inflammatory macrophages and fibrosis. The calcium-activated potassium channel type 3.1 (K<sub>Ca</sub&g...

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Bibliographic Details
Main Authors: Marta Morotti, Stefano Garofalo, Germana Cocozza, Fabrizio Antonangeli, Valeria Bianconi, Chiara Mozzetta, Maria Egle De Stefano, Riccardo Capitani, Heike Wulff, Cristina Limatola, Myriam Catalano, Francesca Grassi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Life
Subjects:
Duchenne muscular dystrophy
macrophages
fibroblasts
fibrosis
Kcnn4
K<sub>Ca</sub>3.1
Online Access:https://www.mdpi.com/2075-1729/12/4/538

Internet

https://www.mdpi.com/2075-1729/12/4/538

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