Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1

Enrichment of Cxcl12 promoter with TET2: A possible link between promoter demethylation and enhanced gene expression in the absence of PARP-1

Previously, we described the link between C-X-C motif chemokine 12 (Cxcl12) gene induction and DNA hypomethylation in the absence of poly(ADP-ribose) polymerase 1 (PARP-1). We have now firmly established that demethylation is the primary cause of gene induction on the basis of Cxcl12 gene upregulati...

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Bibliographic Details
Main Authors: Tolić Anja Z., Rajić Jovana J., Đorđević Marija B., Đorđević Miloš M., Dinić Svetlana S., Grdović Nevena M., Arambašić-Jovanović Jelena D., Mihailović Mirjana V., Poznanović Goran Đ., Jurkowski Tomasz P., Vidaković Melita S., Uskoković Aleksandra S.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2019-01-01
Series:Archives of Biological Sciences
Subjects:
dna demethylation
5-aza
tet2
parp-1
cxcl12
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2019/0354-46641900027T.pdf

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http://www.doiserbia.nb.rs/img/doi/0354-4664/2019/0354-46641900027T.pdf

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