Blood Pressure-Lowering Effect of Wine Lees Phenolic Compounds Is Mediated by Endothelial-Derived Factors: Role of Sirtuin 1

The antihypertensive effect of wine lees powder (WLPW) from a Cabernet grape variety was related to its high content in flavanols and anthocyanins compounds. This study investigates the involvement of endothelial-derived factors and SIRT1 in its bioactivity. Spontaneously hypertensive rats (SHR) wer...

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Bibliographic Details
Main Authors: Raúl López-Fernández-Sobrino, Jorge R. Soliz-Rueda, Javier Ávila-Román, Anna Arola-Arnal, Manuel Suárez, Begoña Muguerza, Francisca Isabel Bravo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/10/7/1073