Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice

Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) overdose is one of the major causes of acute liver failure. Severe liver inflammation and the production of oxidative stress occur due to toxic APAP metabolites and glutathione depletion. Growing evidence has proved that vitamin D (VD) exerts anti-inflammatory and antioxidative...

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Bibliographic Details
Main Authors: Supachaya Sriphoosanaphan, Pakkapon Rattanachaisit, Kanjana Somanawat, Natcha Wanpiyarat, Piyawat Komolmit, Duangporn Werawatganon
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biomedicines
Subjects:
vitamin D
calcitriol
acetaminophen
APAP
hepatotoxicity
liver injury
Online Access:https://www.mdpi.com/2227-9059/11/6/1534

Internet

https://www.mdpi.com/2227-9059/11/6/1534

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