Evaluation of cytotoxic effects of several novel tetralin derivatives against Hela, MDA-MB-468, and MCF-7 cancer cells

Evaluation of cytotoxic effects of several novel tetralin derivatives against Hela, MDA-MB-468, and MCF-7 cancer cells

Background: The inhibitors of the enzymes estrone sulfatase and 17-β-hydroxysteroid dehydrogenase (17-β-HSD) could provide a means of blocking estrogen biosynthesis leading to regression of estrogen-dependent tumors. We evaluated the cytotoxicity of several tetralin derivatives, 2-(4-halo-phenylmeth...

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Bibliographic Details
Main Authors: Fateme Shafiee, Hojjat Sadeghi-aliabadi, Farshid Hassanzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Advanced Biomedical Research
Subjects:
Cytotoxicity
tetralin derivatives
17-β-HSD
estrone sulfatase
Hela
MCF-7
MDA-MB-468
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2012;volume=1;issue=1;spage=76;epage=76;aulast=Shafiee

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2012;volume=1;issue=1;spage=76;epage=76;aulast=Shafiee

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