Bone Remodeling Markers in Children with Acute Lymphoblastic Leukemia after Intensive Chemotherapy: The Screenshot of a Biochemical Signature

Bone Remodeling Markers in Children with Acute Lymphoblastic Leukemia after Intensive Chemotherapy: The Screenshot of a Biochemical Signature

Purpose: to investigate the effects of intensive chemotherapy and glucocorticoid (GC) treatment on bone remodeling markers in children with acute lymphoblastic leukemia (ALL). Methods: A cross-sectional study was carried out in 39 ALL children (aged 7.64 ± 4.47) and 49 controls (aged 8.7 ± 4.7 years...

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Bibliographic Details
Main Authors: Paola Muggeo, Massimo Grassi, Vito D’Ascanio, Vincenzo Brescia, Antonietta Fontana, Laura Piacente, Francesca Di Serio, Paola Giordano, Maria Felicia Faienza, Nicola Santoro
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cancers
Subjects:
acute lymphoblastic leukemia (ALL)
bone remodeling
bone biomarkers
nuclear factor kappa-B ligand (RANKL)
osteoprotegerin (OPG)
Wnt/β-catenin
Online Access:https://www.mdpi.com/2072-6694/15/9/2554

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https://www.mdpi.com/2072-6694/15/9/2554

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