Ricin Toxin Activates the NALP3 Inflammasome

Ricin exhibits well characterized ribotoxic actions that lead to the inhibition of protein synthesis and the phosphorylation of stress activated protein kinases (SAPKs). Proinflammatory effects of ricin are thought to be caused by upregulation of genes encoding proinflammatory transcripts as a resul...

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Bibliographic Details
Main Authors: Meghan Lindauer, John Wong, Bruce Magun
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/2/6/1500/