Ricin Toxin Activates the NALP3 Inflammasome
Ricin exhibits well characterized ribotoxic actions that lead to the inhibition of protein synthesis and the phosphorylation of stress activated protein kinases (SAPKs). Proinflammatory effects of ricin are thought to be caused by upregulation of genes encoding proinflammatory transcripts as a resul...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-06-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/2/6/1500/ |