Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals

Memory CD8+ T Cell Protection From Viral Reinfection Depends on Interleukin-33 Alarmin Signals

Memory CD8+ cytotoxic T lymphocytes (CTLs) can protect against viral reinfection. However, the signals driving rapid memory CTL reactivation have remained ill-defined. Viral infections can trigger the release of the alarmin interleukin-33 (IL-33) from non-hematopoietic cells. IL-33 signals through i...

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Bibliographic Details
Main Authors: Claudia Baumann, Anja Fröhlich, Tobias M. Brunner, Vivien Holecska, Daniel D. Pinschewer, Max Löhning
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
IL-33
ST2
CD8+ T cells
alarmins
adaptive memory
virus infection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01833/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01833/full

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