The role of the blood-brain barrier in the development and treatment of migraine and other pain disorders

The function of the blood-brain barrier (BBB) related to chronic pain has been explored by its classical role in regulating the transcellular and paracellular transport, thus controlling the flow of drugs that act at the central nervous system, such as the opioid analgesics (e.g., morphine) and non-...

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Bibliographic Details
Main Authors: Marcos Fabio DosSantos, Rosenilde Carvalho Holanda-Afonso, Rodrigo Lopes Lima, Alexandre F DaSilva, Vivaldo eMoura-Neto
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00302/full