Distinct spatial landscapes in clear-cell renal cell carcinoma as revealed by whole transcriptome analysis

Background: Clear-cell renal cell carcinoma (ccRCC) is the most common and aggressive form of renal cancer and a paradigm of inter- and intratumor heterogeneity. We carried out an exploratory digital spatial profiling of the tumor interior and periphery of two ccRCC tumor specimens and mapped spatia...

Full description

Bibliographic Details
Main Authors: J.I. López, M.F. Hogan, B. Sutton, S.E. Church, J.C. Angulo, C.E. Nunes-Xavier
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Immuno-Oncology and Technology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018823003763