Identification of two novel autism genes, TRPC4 and SCFD2, in Qatar simplex families through exome sequencing

Identification of two novel autism genes, TRPC4 and SCFD2, in Qatar simplex families through exome sequencing

This study investigated the genetic underpinnings of autism spectrum disorder (ASD) in a Middle Eastern cohort in Qatar using exome sequencing. The study identified six candidate autism genes in independent simplex families, including both four known and two novel autosomal dominant and autosomal re...

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Bibliographic Details
Main Authors: Vijay Gupta, Afif Ben-Mahmoud, Bonsu Ku, Dinesh Velayutham, Zainab Jan, Abdi Yousef Aden, Ahmad Kubbar, Fouad Alshaban, Lawrence W. Stanton, Puthen Veettil Jithesh, Lawrence C. Layman, Hyung-Goo Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Psychiatry
Subjects:
exome sequencing
autism
intellectual disability
digenic
TRPC4
SCFD2
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1251884/full

Internet

https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1251884/full

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