Down syndrome: Distribution of brain amyloid in mild cognitive impairment

Down syndrome: Distribution of brain amyloid in mild cognitive impairment

Abstract Introduction Down syndrome (DS) is associated with a higher risk of dementia. We hypothesize that amyloid beta (Aβ) in specific brain regions differentiates mild cognitive impairment in DS (MCI‐DS) and test these hypotheses using cross‐sectional and longitudinal data. Methods 18F‐AV‐45 (flo...

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Bibliographic Details
Main Authors: David B. Keator, Michael J. Phelan, Lisa Taylor, Eric Doran, Sharon Krinsky‐McHale, Julie Price, Erin E. Ballard, William C. Kreisl, Christy Hom, Dana Nguyen, Margaret Pulsifer, Florence Lai, Diana H. Rosas, Adam M. Brickman, Nicole Schupf, Michael A. Yassa, Wayne Silverman, Ira T. Lott
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Subjects:
ABC‐DS
ADDS
Alzheimer's disease
amyloid
AV‐45
dementia
Online Access:https://doi.org/10.1002/dad2.12013

Internet

https://doi.org/10.1002/dad2.12013

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