Association between the CYP2B6 polymorphisms and nonnucleoside reverse transcriptase inhibitors drug-induced liver injury: a systematic review and meta-analysis

Association between the CYP2B6 polymorphisms and nonnucleoside reverse transcriptase inhibitors drug-induced liver injury: a systematic review and meta-analysis

Abstract Nevirapine (NVP) and Efavirenz (EFV) can cause antiretroviral drug-induced liver injury (ARVDILI). The objectives of this study were to summarize and analyze existing data on pharmacogenomics associated with nonnucleoside reverse transcriptase inhibitors drug-induced liver injury using syst...

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Bibliographic Details
Main Authors: Noppadol Chanhom, Janjira Sonjan, Jarupat Inchai, Wanvisa Udomsinprasert, Usa Chaikledkaew, Supharat Suvichapanich, Surakameth Mahasirimongkol, Jiraphun Jittikoon
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Drug-induced liver injury
CYP2B6
Human immunodeficiency virus
Hepatotoxicity
Systematic review
Meta-analysis
Online Access:https://doi.org/10.1038/s41598-024-79965-0

Internet

https://doi.org/10.1038/s41598-024-79965-0

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