Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes

Leukocytes and other amoeboid cells change shape as they move, forming highly dynamic, actin-filled pseudopods. Although we understand much about the architecture and dynamics of thin lamellipodia made by slow-moving cells on flat surfaces, conventional light microscopy lacks the spatial and tempora...

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Bibliographic Details
Main Authors: Lillian K Fritz-Laylin, Megan Riel-Mehan, Bi-Chang Chen, Samuel J Lord, Thomas D Goddard, Thomas E Ferrin, Susan M Nicholson-Dykstra, Henry Higgs, Graham T Johnson, Eric Betzig, R Dyche Mullins
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
cell migration
microscopy
visualization
actin
arp2/3
amoeboid motility
Online Access:https://elifesciences.org/articles/26990

Internet

https://elifesciences.org/articles/26990

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