The Highly Productive <i>Thermothelomyces heterothallica</i> C1 Expression System as a Host for Rapid Development of Influenza Vaccines

The Highly Productive <i>Thermothelomyces heterothallica</i> C1 Expression System as a Host for Rapid Development of Influenza Vaccines

(1) Influenza viruses constantly change and evade prior immune responses, forcing seasonal re-vaccinations with updated vaccines. Current FDA-approved vaccine manufacturing technologies are too slow and/or expensive to quickly adapt to mid-season changes in the virus or to the emergence of pandemic...

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Bibliographic Details
Main Authors: Gabor Keresztes, Mark Baer, Mark R. Alfenito, Theo C. Verwoerd, Andriy Kovalchuk, Marilyn G. Wiebe, Tor Kristian Andersen, Markku Saloheimo, Ronen Tchelet, Richard Kensinger, Gunnveig Grødeland, Mark Emalfarb
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Vaccines
Subjects:
<i>T</i><i>hermothelomyces heterothallica</i> C1
recombinant protein expression
influenza vaccine
filamentous fungi
trimeric influenza hemagglutinin
targeted influenza hemagglutinin
Online Access:https://www.mdpi.com/2076-393X/10/2/148

Internet

https://www.mdpi.com/2076-393X/10/2/148

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