The hepatokine TSK maintains myofiber integrity and exercise endurance and contributes to muscle regeneration

Mammalian skeletal muscle contains heterogenous myofibers with different contractile and metabolic properties that sustain muscle mass and endurance capacity. The transcriptional regulators that govern these myofiber gene programs have been elucidated. However, the hormonal cues that direct the spec...

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Bibliographic Details
Main Authors: Qiuyu Wang, Xiaoxue Qiu, Tongyu Liu, Cheehoon Ahn, Jeffrey F. Horowitz, Jiandie D. Lin
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-02-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.154746