Identifying well-folded de novo proteins in the new era of accurate structure prediction

Computational de novo protein design tailors proteins for target structures and oligomerisation states with high stability, which allows overcoming many limitations of natural proteins when redesigned for new functions. Despite significant advances in the field over the past decade, it remains chall...

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Bibliographic Details
Main Authors: Daniel Peñas-Utrilla, Enrique Marcos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.991380/full