Two New 1,3,4-Oxadiazoles With Effective Antifungal Activity Against Candida albicans

Two New 1,3,4-Oxadiazoles With Effective Antifungal Activity Against Candida albicans

Candida infections have become a serious public health problem with high mortality rates, especially in immunocompromised patients, since Candida albicans is the major opportunistic pathogen responsible for systemic or invasive candidiasis. Commercially available antifungal agents are restricted and...

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Bibliographic Details
Main Authors: Isis Regina Grenier Capoci, Karina Mayumi Sakita, Daniella Renata Faria, Franciele Abigail Vilugron Rodrigues-Vendramini, Glaucia Sayuri Arita, Admilton Gonçalves de Oliveira, Maria Sueli Felipe, Bernard Maigret, Patricia de Souza Bonfim-Mendonça, Erika Seki Kioshima, Terezinha Inez Estivalet Svidzinski
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
thioredoxin reductase
in vitro
in vivo
antifungal activity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02130/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02130/full

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