Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

The neural crest (NC) is an important multipotent embryonic cell population and its impaired specification leads to various developmental defects, often in an anteroposterior (A-P) axial level-specific manner. The mechanisms underlying the correct A-P regionalisation of human NC cells remain elusive...

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Bibliographic Details
Main Authors: Antigoni Gogolou, Celine Souilhol, Ilaria Granata, Filip J Wymeersch, Ichcha Manipur, Matthew Wind, Thomas JR Frith, Maria Guarini, Alessandro Bertero, Christoph Bock, Florian Halbritter, Minoru Takasato, Mario R Guarracino, Anestis Tsakiridis
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
axial identity
brachyury
Hox
neuromesodermal progenitors
neural crest
embryonic stem cells
Online Access:https://elifesciences.org/articles/74263

Internet

https://elifesciences.org/articles/74263

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