Transient Receptor Potential Ankyrin 1 Ion Channel Is Expressed in Osteosarcoma and Its Activation Reduces Viability

Transient Receptor Potential Ankyrin 1 Ion Channel Is Expressed in Osteosarcoma and Its Activation Reduces Viability

Osteosarcoma is a highly malignant, painful cancer with poor treatment opportunities and a bad prognosis. Transient receptor potential ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1) receptors are non-selective cation channels that have been of great interest in cancer, as their expression is increased in...

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Bibliographic Details
Main Authors: Lina Hudhud, Katalin Rozmer, Angéla Kecskés, Krisztina Pohóczky, Noémi Bencze, Krisztina Buzás, Éva Szőke, Zsuzsanna Helyes
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
osteosarcoma
TRPA1
TRPV1
mustard oil
capsaicin
RNAscope in situ hybridization
Online Access:https://www.mdpi.com/1422-0067/25/7/3760

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https://www.mdpi.com/1422-0067/25/7/3760

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