Proposal for considerations during human iPSC-derived cardiac organoid generation for cardiotoxicity drug testing

Proposal for considerations during human iPSC-derived cardiac organoid generation for cardiotoxicity drug testing

Human iPSC-derived cardiac organoids (hiPSC-COs) for cardiotoxicity drug testing via the variety of cell lines and unestablished protocols may lead to differences in response results due to a lack of criteria for generation period and size. To ensure reliable drug testing, it is important for resear...

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Bibliographic Details
Main Authors: Sang Woo Lee, MyeongJin Song, Dong-Hun Woo, Gi Seok Jeong
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cardiotoxicity drug testing
Human iPSC
Cardiac Organoid
Generation Period
Size
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224003950

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http://www.sciencedirect.com/science/article/pii/S0753332224003950

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