Integration of metabolomics and network pharmacology to reveal the protective mechanism underlying Qibai Pingfei capsule on chronic obstructive pulmonary disease

Integration of metabolomics and network pharmacology to reveal the protective mechanism underlying Qibai Pingfei capsule on chronic obstructive pulmonary disease

In this study, we have employed metabolomics technology in combination with network pharmacology to ascertain the key metabolites and hub genes. The objective was to explore the pathway of Qibai Pingfei Capsule (QBPF) in treating COPD through metabolomics. We identified 96 differential metabolites i...

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Bibliographic Details
Main Authors: Jinghui Xie, Mengxiang Liu, Yating Gao, Changan Liu, Fan Wu, Jiabing Tong, Zegeng Li, Jie Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Pharmacology
Subjects:
COPD
Qibai Pingfei capsule
metabolomics
network pharmacology
ferroptosis
glutathione metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1258138/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1258138/full

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