Interferon Alpha-Inducible Protein 27 Expression Is Linked to Disease Severity in Chronic Infection of Both HIV-1 and HIV-2

Interferon Alpha-Inducible Protein 27 Expression Is Linked to Disease Severity in Chronic Infection of Both HIV-1 and HIV-2

Disease progression is slower in HIV-2, as compared with HIV-1 infection, in accordance with low or undetectable plasma viremia at viral setpoint. However, it is unclear why most HIV-2 infected individuals are still at risk of developing AIDS. To explore if specific host responses are linked to HIV...

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Bibliographic Details
Main Authors: Angelica A. Palm, Srinivas Veerla, Jacob Lindman, Per-Erik Isberg, Emil Johansson, Antonio Biague, Fredrik Månsson, Hans Norrgren, Joakim Esbjörnsson, Patrik Medstrand, Marianne Jansson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Virology
Subjects:
HIV-1
HIV-2
interferon-stimulated gene (ISG)
viremia
chronic infection
disease severity
Online Access:https://www.frontiersin.org/articles/10.3389/fviro.2022.929053/full

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https://www.frontiersin.org/articles/10.3389/fviro.2022.929053/full

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