The perils of global signal regression for group comparisons: A case study of Autism Spectrum Disorders

We have previously argued from a theoretical basis that the standard practice of regression of the Global Signal from the FMRI time series in functional connectivity studies is ill advised, particularly when comparing groups of participants. Here, we demonstrate in resting-state data from participan...

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Bibliographic Details
Main Authors: Stephen J Gotts, Ziad S Saad, Hang Joon eJo, Gregory L Wallace, Robert W Cox, Alex eMartin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-07-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2013.00356/full