Mechanisms of cell cycle control revealed by a systematic and quantitative overexpression screen in S. cerevisiae.

Regulation of cell cycle progression is fundamental to cell health and reproduction, and failures in this process are associated with many human diseases. Much of our knowledge of cell cycle regulators derives from loss-of-function studies. To reveal new cell cycle regulatory genes that are difficul...

Full description

Bibliographic Details
Main Authors: Wei Niu, Zhihua Li, Wenjing Zhan, Vishwanath R Iyer, Edward M Marcotte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2438615?pdf=render