Biophysical and chemical stability of surfactant/budesonide and the pulmonary distribution following intra-tracheal administration

Intra-tracheal instillation of budesonide using surfactant as a vehicle significantly decreased the incidence of bronchopulmonary dysplasia or death in preterm infants. The formularity of surfactant supplemented with budesonide and biophysical and chemical stability of the suspension has not been we...

Full description

Bibliographic Details
Main Authors: Chung-Ming Chen, Chien-Hsiang Chang, Chih-Hua Chao, Mei-Hui Wang, Tsu-Fu Yeh
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2019.1618418