In Vivo Genotoxicity of Gold Nanorods in Mouse Bone Marrow Compared with Cyclophosphamide

In Vivo Genotoxicity of Gold Nanorods in Mouse Bone Marrow Compared with Cyclophosphamide

Gold nanorods (GNRs) are now under extensive investigation for biomedical applications. The in vivo genotoxic profile GNRs are not elucidated yet, therefore we investigated it in comparison with one of the most effective chemotherapeutic agents, cyclophosphamide (CP), in a mice model. PEGylated-GNRs...

Full description

Bibliographic Details
Main Authors: Amira M. Gamal-Eldeen, Mona A.M. Abo-Zeid, Sherien M. El-Daly, Mahmoud T. Abo-Elfadl, Cinderella A. Fahmy, Moustafa R.K. Ali, Mostafa A. El-Sayed
Format: Article
Language:English
Published: Tsinghua University Press 2016-12-01
Series:Nano Biomedicine and Engineering
Subjects:
gold-nanorods
cyclophosphamide
dna damage
genotoxicity
chromosome aberrations
micronucleus
comet assay
Online Access:https://www.sciopen.com/article/10.5101/nbe.v8i4.p306-314

Internet

https://www.sciopen.com/article/10.5101/nbe.v8i4.p306-314

Similar Items