Parathyroid Hormone Promotes Human Umbilical Vein Endothelial Cell Migration and Proliferation Through Orai1-Mediated Calcium Signaling

Parathyroid Hormone Promotes Human Umbilical Vein Endothelial Cell Migration and Proliferation Through Orai1-Mediated Calcium Signaling

Parathyroid hormone is the main endocrine regulator of extracellular calcium and phosphorus levels. Secondary hyperparathyroidism–induced endothelial dysfunction may be related to calcium homeostasis disorders. Here, we investigated the effects of parathyroid hormone on human umbilical vein endothel...

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Bibliographic Details
Main Authors: Shuhao Wang, Lijie Xu, Yv Wu, Hailong Shen, Zhangying Lin, Yang Fang, Lesha Zhang, Bing Shen, Yehai Liu, Kaile Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
secondary hyperparathyroidism
parathyroid hormone
store-operated Ca2+ entry
human umbilical vein endothelial cells
COL1A1
NFAT
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.844671/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.844671/full

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